Recommended Guidelines for Perinatal Care in Illinois June 2004


Recommended Guidelines for Perinatal Care in Illinois June 2004

Chromosome Abnormalities in Liveborns

Maternal Age Risk for Down >s Syndrome Total Risk for Chromosomal Abnormalities
20 1/1,667 1/526
21 1/1,667 1/526
22 1/1,429 1/500
23 1/1,429 1/500
24 1/1,250 1/476
25 1/1,250 1/476
26 1/1,176 1/476
27 1/1,111 1/455
28 1/1,053 1/435
29 1/1,000 1/417
30 1/952 1/385
31 1/909 1/385
32 1/769 1/322
33 1/602 1/286
34 1/485 1/238
35 1/378 1/192
36 1/289 1/156
37 1/224 1/127
38 1/173 1/102
39 1/136 1/83
40 1/106 1/66

Source:Hooks, et. al. Table 3.2, "Chromosome Abnormalities in Liveborns," in Guidelines for Perinatal Care, 3rd edition, American Academy of Pediatrics, American College of Obstetricians and Gynecologists, and March of Dimes Birth Defects Foundation.

The objective for pre-conception/ inter-conception care is ultimately to reduce Infant mortality.