Addendum 4.2.2 APORS Case Definition

Gestational age less than 31 completed weeks (based on physician's assessment)

Multiple birth, triplets or higher order

Death (fetal death or death before discharge from the newborn stay)

Prenatal drug exposure

  • Diagnosis of a positive toxicology for any drug (except marijuana or drugs administered during labor and delivery)
  • Signs of drug toxicity or withdrawal (in the infant)
  • Children of mothers who admit to illicit drug use during this pregnancy (except marijuana)

Birth defect or congenital anomaly

(except as listed below)

Congenital pigment anomalies

(stork bites, Mongolian spots etc.)

Dacrostenosis

Incomplete or redundant penile foreskin

Isolated choroid plexus cyst

Isolated simian crease

Patent ductus arteriosus (PDA)

Patent foraman ovale (PFO)

Peripheral pulmonic stenosis (PPS)

Persistent fetal circulation

Polydactyly

Preauricular sinus

Prenatal diagnosis of hydronephrosis,

caliectasis or pelviectasis

Sacral dimple with visualized base or post-natal imaging ruling out a problem

Skin tag

Syndactyly

Tongue tie

Two-vessel cord

Umbilical hernia

Undescended testes

Vascular harmatomas (small or insignificant birth marks, port wine stains, strawberry nevi etc.)

Serious congenital infections

(Excludes: Hepatitis C or HIV exposure, neonatal candidiasis (thrush), conjunctivitis, dacrocystitis, infective mastitis and omphalitis, and HIV.)

Chlamydia

Confirmed septicemia (sepsis)

Cytomegalovirus

Gonococcal conjunctivitis neonatorium

Group B streptococcus

Hepatitis B (disease or perinatal exposure)

Herpes

Listeriosis

Meningitis

Necrotizing enterocolitis leading to surgery

Rubella

Syphilis

Tetanus neonatorum

Endocrine, metabolic or immune disorders

Adrenogenital syndrome
Combined immunity deficiency
Cystic Fibrosis
Inborn errors of metabolism

Blood disorder

Coagulation defects
Constitutional aplastic anemia
Hereditary hemolytic anemia
Leukemia

Other conditions

Bronchopulmonary dysplasia

Cerebral lipidoses

Chorioretinitis

Conditions leading to ECMO

Conditions leading to > 72 hours on a ventilator

Endocardial fibroelastosis

Erb's palsy

Fetal alcohol syndrome

HIE leading to cooling treatment

Intrauterine growth restriction leading to SGA

IVH grade III or IV

Neurofibromatosis

Occlusion of cerebral arteries

Retinopathy of prematurity

Strabismus

Seizures

Effective 1/1/13

Revised 2/9/18